Article
Association of the mSin3A-histone deacetylase 1/2 corepressor complex with the mouse steroidogenic acute regulatory protein gene.
Molecular endocrinology (Baltimore, Md.) - 1 Jan 2006
Clem Brian F, Clark Barbara J
Abstract excerpt
Several factors have been identified in the transcriptional repression of the steroidogenic acute regulatory protein (StAR) gene promoter; yet, no associating corepressor complexes have been characterized for the mouse promoter in MA-10 mouse Leydig tumor cells. We now report that Sp3, CAGA element binding proteins, and a corepressor complex consisting of mSin3A, histone deacetylase (HDAC)1, and HDAC2 associates...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
