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Article

Histone-dependent association of Tup1-Ssn6 with repressed genes in vivo.

Molecular and cellular biology - 1 Feb 2002

Davie Judith K, Trumbly Robert J, Dent Sharon Y R

Abstract excerpt

The Tup1-Ssn6 complex regulates diverse classes of genes in Saccharomyces cerevisiae and serves as a model for corepressor functions in many organisms. Tup1-Ssn6 does not directly bind DNA but is brought to target genes through interactions with sequence-specific DNA binding factors. Full repression by Tup1-Ssn6 appears to require interactions with both the histone tails and components of the general...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11784848
DOI: 10.1128/MCB.22.3.693-703.2002
PMCID: PMC133554

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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