Article
Characterization of the WAVE1 knock-out mouse: implications for CNS development.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Apr 2003
Dahl John P, Wang-Dunlop Jeanne, Gonzales Cathleen, Goad Mary E P, Mark Robert J, Kwak Seung P
Abstract excerpt
Developing neurons must respond to a wide range of extracellular signals during the process of brain morphogenesis. One mechanism through which immature neurons respond to such signals is by altering cellular actin dynamics. A recently discovered link between extracellular signaling events and the actin cytoskeleton is the WASP/WAVE (Wiscott-Aldrich Syndrome protein/WASP-family verprolin-homologous protein)...
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