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Article

Restricted morphological and behavioral abnormalities following ablation of β-actin in the brain.

PloS one - 1 Jan 2012

Cheever Thomas R, Li Bin, Ervasti James M

Abstract excerpt

The local translation of β-actin is one mechanism proposed to regulate spatially-restricted actin polymerization crucial for nearly all aspects of neuronal development and function. However, the physiological significance of localized β-actin translation in neurons has not yet been demonstrated in vivo. To investigate the role of β-actin in the mammalian central nervous system (CNS), we characterized brain...

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Identifiers

PMID: 22403730
DOI: 10.1371/journal.pone.0032970
PMCID: PMC3293915

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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