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Article

ACE Gene Polymorphism and Losartan Treatment in Type 2 Diabetic Patients With Nephropathy

16 Jan 2008

Abstract excerpt

Losartan treatment reduced renal outcomes in proteinuric patients with type 2 diabetes in the Reduction of Endpoints in NIDDM with the Angiotensin II Antagonist Losartan (RENAAL) study. It is unknown whether an insertion (I)/deletion (D) polymorphism in the angiotensin I-converting enzyme (ACE) gene predicts renal outcomes and death and influences the effect of losartan in these patients. Pharmacogenetic analyses...

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PMID: 18199798
DOI: 10.1681/asn.2007050582

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ACE Gene Polymorphism and Losartan Treatment in Type 2 Diabetic Patients With NephropathyPMID 18199798Read ↗

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