Article
Evaluating the context-dependent effect of family history of stroke in a genome scan for hypertension.
Stroke - 1 May 2003
Morrison Alanna C, Brown Andrew, Kardia Sharon L R, Turner Stephen T, Boerwinkle Eric
Abstract excerpt
BACKGROUND AND PURPOSE: Hypertension is an important risk factor for stroke, and the 2 diseases may share susceptibility genes in common. We sought to identify genomic regions influencing susceptibility to both hypertension and stroke. SUBJECTS AND METHODS: Genome-wide linkage scans were performed in samples of 338 white and 265 black hypertensive sibships recruited by the Genetic Epidemiology Network of...
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