Article
Meta-analysis of genome-wide scans for hypertension and blood pressure in Caucasians shows evidence of susceptibility regions on chromosomes 2 and 3.
Human molecular genetics - 1 Oct 2004
Koivukoski Liisa, Fisher Sheila A, Kanninen Timo, Lewis Cathryn M, von Wowern Fredrik, Hunt Steven, Kardia Sharon L R, Levy Daniel, Perola Markus, Rankinen Tuomo, Rao Dabeeru C, Rice Treva, Thiel Bonnie A, Melander Olle
Abstract excerpt
Individual genome-wide scans of blood pressure (BP) and hypertension (HT) have shown inconsistent results. The aim of this study was to investigate whether there was any consistent evidence of linkage across multiple studies with similar ethnicity. We applied the genome-search meta-analysis method (GSMA) to nine published genome-wide scans of BP (n = 5) and HT (n = 4) from Caucasian populations. For each study,...
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