Article
Genetic predisposition to stroke in relatives of hypertensives.
Stroke - 1 Feb 2000
Nicolaou M, DeStefano A L, Gavras I, Cupples L A, Manolis A J, Baldwin C T, Gavras H, Farrer L A
Abstract excerpt
BACKGROUND AND PURPOSE: The genetic basis of stroke is poorly understood. We evaluated patterns of familial aggregation of hypertension and stroke to test the hypothesis that inherited susceptibility to these disorders may be determined by a common set of factors. METHODS: Genealogical and medical history information was obtained for a cohort of 354 hypertensive probands ascertained in a clinic-based setting,...
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