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Article

A novel cytidine deaminase AIDs in the delivery of error-prone polymerases to immunoglobulin genes.

DNA repair - 13 May 2003

Diaz Marilyn, Storb Ursula

Abstract excerpt

Immunoglobulin genes undergo somatic hypermutation in activated B lymphocytes. The mutations are targeted to the variable region of the gene, apparently by co-transcriptional deposition of a mutation complex. The novel activation induced deaminase (AID) gene is required for this process and recent work indicates that it is the cytidine deaminase activity of the AID protein rather than an associated RNA editing...

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Share to AICDA (Activation-Induced Cytidine Deaminase)
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Identifiers

PMID: 12713818
DOI: 10.1016/s1568-7864(02)00240-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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