Article
Genome-wide association study of recurrent early-onset major depressive disorder.
Molecular psychiatry - 1 Feb 2011
Shi J, Potash J B, Knowles J A, Weissman M M, Coryell W, Scheftner W A, Lawson W B, DePaulo J R, Gejman P V, Sanders A R, Johnson J K, Adams P, Chaudhury S, Jancic D, Evgrafov O, Zvinyatskovskiy A, Ertman N, Gladis M, Neimanas K, Goodell M, Hale N, Ney N, Verma R, Mirel D, Holmans P, Levinson D F
Abstract excerpt
A genome-wide association study was carried out in 1020 case subjects with recurrent early-onset major depressive disorder (MDD) (onset before age 31) and 1636 control subjects screened to exclude lifetime MDD. Subjects were genotyped with the Affymetrix 6.0 platform. After extensive quality control procedures, 671 424 autosomal single nucleotide polymorphisms (SNPs) and 25 068 X chromosome SNPs with minor allele...
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