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Article

Assessment of clonality in T-cell large granular lymphocytic leukemia: flow cytometric T cell receptor Vβ repertoire and T cell receptor gene rearrangement.

Leukemia & lymphoma - 1 Feb 2015

Qiu Zhi-Yuan, Shen Wen-Yi, Fan Lei, Wang Li, Yu Hui, Qiao Chun, Wu Yu-Jie, Lu Rui-Nan, Qian Jun, He Guang-Sheng, Xu Wei, Li Jian-Yong

Abstract excerpt

The usefulness of flow cytometric variable β-chain repertoire (FC-Vβ) and T-cell receptor gene rearrangement (TCR-GR) analyses for differentiating T-cell large granular lymphocytic leukemia (T-LGLL) from reactive T-large granular lymphocyte (T-LGL) lymphocytosis has been insufficiently studied to date. In this study, we analyzed the diagnostic value of TCR-GR and FC-Vβ analysis in T-LGLL, and compared these...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24828862
DOI: 10.3109/10428194.2014.921297

Genes

STAT3

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