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Diagnostic role of tests for T cell receptor (TCR) genes

23 Dec 2002

Abstract excerpt

Rapid advances in molecular biological techniques have made it possible to study disease pathogenesis at a genomic level. T cell receptor (TCR) gene rearrangement is an important event in T cell ontogeny that enables T cells to recognise antigens specifically, and any dysregulation in this complex yet highly regulated process may result in disease. Using techniques such as Southern blot hybridisation, polymerase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 12499424
DOI: 10.1136/jcp.56.1.1

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