Article
Resolving T-cell receptor clonality in two and genotype in four multiplex polymerase chain reactions.
Haematologica - 1 Nov 2005
Dictor Michael, Warenholt Janina, Isinger Anna
Abstract excerpt
BACKGROUND AND OBJECTIVES: The diagnosis of T-cell neoplasia requires the use of immunohistochemistry on tumor sections or molecular genetic analysis of T-cell receptor (TCR) clonality. Multiplex polymerase chain reactions (PCR) offer a sensitive and expeditious approach to determining clonality early in the diagnostic work-up. We determined the sensitivity and specificity of four multiple PCR for genotyping...
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