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Article

Complementarity-determining region 3 spectratyping analysis of the TCR repertoire in multiple sclerosis.

Journal of immunology (Baltimore, Md. : 1950) - 1 May 2003

Matsumoto Yoh, Yoon Wong Kee, Jee Youngheun, Fujihara Kazuo, Misu Tatsuro, Sato Shigeru, Nakashima Ichiro, Itoyama Yasuto

Abstract excerpt

Multiple sclerosis (MS) is considered to be an autoimmune disease mediated by T cells reactive with Ags in the CNS. Therefore, it has been postulated that neuroantigen-reactive T cells bearing particular types of TCRs are expanded clonally during the course of the disease. However, there is a controversy with regard to the TCR usage by T cells associated with the development of MS. By the use of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12707368
DOI: 10.4049/jimmunol.170.9.4846

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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