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Article

Expression and Function of the Trypanosoma brucei Major Surface Protease (GP63) Genes

29 Jun 2003

Abstract excerpt

The genome of the African trypanosome Trypanosoma brucei (Tb) contains at least three gene families (TbMSP-A, -B, and -C) encoding homologues of the abundant major surface protease (MSP, previously called GP63), which is found in all Leishmania species. TbMSP-B mRNA occurs in both procyclic and bloodstream trypanosomes, whereas TbMSP-A and -C mRNAs are detected only in bloodstream organisms. RNA interference...

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PMID: 12707278
DOI: 10.1074/jbc.m301451200

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