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Article

Mutational analysis of the variant surface glycoprotein GPI-anchor signal sequence in Trypanosoma brucei.

Journal of cell science - 15 Feb 2002

Böhme Ulrike, Cross George A M

Abstract excerpt

The variant surface glycoproteins (VSG) of Trypanosoma brucei are anchored to the cell surface via a glycosylphosphatidylinositol (GPI) anchor. All GPI-anchored proteins are synthesized with a C-terminal signal sequence, which is replaced by a GPI-anchor in a rapid post-translational transamidation reaction. VSG GPI signal sequences are extraordinarily conserved. They contain either 23 or 17 amino acids, a...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11865036
DOI: 10.1242/jcs.115.4.805

Genes

GPI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutational analysis of the variant surface glycoprotein GPI-anchor signal sequence in Trypanosoma brucei.PMID 11865036Read ↗

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