Article
The -295T-to-C promoter polymorphism of the IL-16 gene is associated with Crohn's disease.
Clinical immunology (Orlando, Fla.) - 1 Mar 2003
Glas J, Török H P, Unterhuber H, Radlmayr M, Folwaczny C
Abstract excerpt
Recently, a T-to-C polymorphism at position -295 in the promoter region of the human interleukin-16 (IL-16) gene was reported. The expression of IL-16 is increased in inflammatory bowel disease, in particular in Crohn's disease. However, data concerning the IL-16 promoter polymorphism in inflammatory bowel disease are lacking. Thus, the current study aimed at the assessment of this polymorphism in Crohn's disease...
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