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Article

Interleukin-16 (IL-16) gene polymorphisms in Iranian patients with colorectal cancer.

Journal of gastrointestinal and liver diseases : JGLD - 1 Dec 2011

Azimzadeh Pedram, Romani Sara, Mohebbi Seyed Reza, Kazemian Shabnam, Vahedi Mohsen, Almasi Shohreh, Fatemi Seyed Reza, Zali Mohammad Reza

Abstract excerpt

BACKGROUND AND AIMS: A number of theories have been put forward to clarify the etiology of colorectal cancer (CRC), such as genetic alterations and cytokine production. A combination of inflammatory cytokines has an important role in cancer development. The aim of our study was to screen for alterations located in promoter and exons of IL-16 gene sequence, to determine the distribution of genotypes in individuals...

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PMID: 22187702

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