Article
Role of heparan sulfate for attachment and entry of tick-borne encephalitis virus.
Virology - 30 Mar 2003
Kroschewski Helga, Allison Steven L, Heinz Franz X, Mandl Christian W
Abstract excerpt
Attachment of the flavivirus tick-borne encephalitis (TBE) virus to different permissive cell lines was investigated by a newly established quantitative assay using fluorescence-labeled virus. Previous work had shown that BHK-21 cell-adapted mutants of TBE virus had acquired potential heparan sulfate (HS) binding sites on the outer surface of protein E. Quantitative analysis of one of these mutants indicated that...
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