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Article

Topoisomerase IV mutations in quinolone-resistant salmonellae selected in vitro.

Microbial drug resistance (Larchmont, N.Y.) - 1 Jan 2003

Hansen Heike, Heisig Peter

Abstract excerpt

The development of high-level fluoroquinolone resistance has rarely been observed in salmonellae and, in contrast to other Gram-negative bacteria mutations affecting topoisomerase IV, a known secondary target of quinolones in Escherichia coli has not been described except for one recent report. The present study used quinolone-susceptible field isolates representing epidemiologically relevant serovars and phage...

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Identifiers

PMID: 12705680
DOI: 10.1089/107662903764736319

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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