Article
Low selection of topoisomerase mutants from strains of Escherichia coli harbouring plasmid-borne qnr genes.
The Journal of antimicrobial chemotherapy - 1 May 2008
Cesaro Annabelle, Bettoni Romain Roth Dit, Lascols Christine, Mérens Audrey, Soussy Claude James, Cambau Emmanuelle
Abstract excerpt
OBJECTIVES: To investigate mutations in the type II topoisomerase genes in quinolone-resistant mutants selected from bacteria harbouring plasmid-borne qnr genes. METHODS: Mutants were selected by nalidixic acid, ciprofloxacin and moxifloxacin from two Escherichia coli reference strains and corres...
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