Article
EGF-dependent and independent activation of MAP kinase during Drosophila oogenesis.
The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology - 1 May 2003
Dammai Vincent, Hsu Tien
Abstract excerpt
Receptor tyrosine kinase (RTK) signaling is involved in multiple cell fate determination during Drosophila oogenesis. To address the problem of signaling specificity, we sought to systematically document the expression pattern of activated MAP kinase, the downstream effector of RTK signaling. We show that MAP kinase is activated in some of the cell types in which Drosophila EGF receptor signaling is known to...
Topics
- Animals
- Cell Differentiation
- Cell Lineage
- Cell Movement
- Drosophila Proteins
- Drosophila melanogaster
- Enzyme Activation
- Epidermal Growth Factor
- ErbB Receptors
- Female
- Germ Cells
- Heat Stress Disorders
- MAP Kinase Signaling System
- Membrane Proteins
- Mitogen-Activated Protein Kinases
- Mutation
- Oocytes
- Oogenesis