The involvement of the Notch locus in Drosophila oogenesis.

doi:10.1242/dev.115.4.913

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Article

The involvement of the Notch locus in Drosophila oogenesis.

Development (Cambridge, England) - 1 Aug 1992

Xu T, Caron L A, Fehon R G, Artavanis-Tsakonas S

Abstract excerpt

The Notch gene in Drosophila encodes a transmembrane protein with homology to EGF that, in a variety of tissues, appears to mediate cell interactions necessary for cell fate choices. Here we demonstrate that oogenesis and spermatogenesis depend on Notch. We examine the phenotypes of the temperature-sensitive Notch allele, Nts1, and, using a monoclonal antibody, determine the cellular and subcellular distribution...

Topics

Animals
Drosophila
Drosophila Proteins
Embryonic Induction
Female
Gene Expression
Genes
Immunohistochemistry
Insect Hormones
Male
Membrane Proteins
Microscopy, Fluorescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oogenesis

Ovary

Phenotype

Receptors, Notch

Spermatogenesis

Testis

Source

Open in PubMed

Identifiers

PMID: 1451667
DOI: 10.1242/dev.115.4.913

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1451667-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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