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Article

The involvement of the Notch locus in Drosophila oogenesis.

Development (Cambridge, England) - 1 Aug 1992

Xu T, Caron L A, Fehon R G, Artavanis-Tsakonas S

Abstract excerpt

The Notch gene in Drosophila encodes a transmembrane protein with homology to EGF that, in a variety of tissues, appears to mediate cell interactions necessary for cell fate choices. Here we demonstrate that oogenesis and spermatogenesis depend on Notch. We examine the phenotypes of the temperature-sensitive Notch allele, Nts1, and, using a monoclonal antibody, determine the cellular and subcellular distribution...

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Source

Identifiers

PMID: 1451667
DOI: 10.1242/dev.115.4.913

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

The involvement of the Notch locus in Drosophila oogenesis.PMID 1451667Read ↗

Adherens junction remodeling by the Notch pathway in Drosophila melanogaster oogenesis.Semantic proximity Read ↗

Role of neurogenic genes in establishment of follicle cell fate and oocyte polarity during oogenesis in Drosophila.Semantic proximity Read ↗

The First Defined Null Allele of the Notch Regulator, a Suppressor of Deltex: Uncovering Its Novel Roles in Drosophila melanogaster Oogenesis.Semantic proximity Read ↗

CoREST acts as a positive regulator of Notch signaling in the follicle cells of Drosophila melanogaster.Semantic proximity Read ↗

Expression of constitutively active Notch arrests follicle cells at a precursor stage during Drosophila oogenesis and disrupts the anterior-posterior axis of the oocyte.Semantic proximity Read ↗

fs (1) Yb is required for ovary follicle cell differentiation in Drosophila melanogaster and has genetic interactions with the Notch group of neurogenic genes.Semantic proximity Read ↗

The daughterless gene functions together with Notch and Delta in the control of ovarian follicle development in Drosophila.Semantic proximity Read ↗

Response to the dorsal anterior gradient of EGFR signaling in Drosophila oogenesis is prepatterned by earlier posterior EGFR activation.Semantic proximity Read ↗

The TGF-beta signaling pathway is essential for Drosophila oogenesis.Semantic proximity Read ↗

EGF-dependent and independent activation of MAP kinase during Drosophila oogenesis.Semantic proximity Read ↗

A dual function of the Notch gene in Drosophila sensillum development.Semantic proximity Read ↗

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