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Article

Modeling and computational analysis of EGF receptor-mediated cell communication in Drosophila oogenesis.

Development (Cambridge, England) - 1 Jun 2002

Shvartsman Stanislav Y, Muratov Cyrill B, Lauffenburger Douglas A

Abstract excerpt

Autocrine signaling through the Epidermal Growth Factor Receptor (EGFR) operates at various stages of development across species. A recent hypothesis suggested that a distributed network of EGFR autocrine loops was capable of spatially modulating a simple single-peaked input into a more complex two-peaked signaling pattern, specifying the formation of a pair organ in Drosophila oogenesis (two respiratory...

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Source

Identifiers

PMID: 12015287
DOI: 10.1242/dev.129.11.2577

Genes

EGFR
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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