Article
The retinoic-like juvenile hormone controls the looping of left-right asymmetric organs in Drosophila.
Development (Cambridge, England) - 1 Jun 2003
Adám Géza, Perrimon Norbert, Noselli Stéphane
Abstract excerpt
In vertebrate development, the establishment of left-right asymmetry is essential for sidedness and the directional looping of organs like the heart. Both the nodal pathway and retinoic acid play major and conserved regulatory roles in these processes. We carried out a novel screen in Drosophila to identify mutants that specifically affect the looping of left-right asymmetric organs. We report the isolation of...
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