Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rargb regulates organ laterality in a zebrafish model of right atrial isomerism.

Developmental biology - 15 Dec 2012

Garnaas Maija K, Cutting Claire C, Meyers Alison, Kelsey Peter B, Harris James M, North Trista E, Goessling Wolfram

Abstract excerpt

Developmental signals determine organ morphology and position during embryogenesis. To discover novel modifiers of liver development, we performed a chemical genetic screen in zebrafish and identified retinoic acid as a positive regulator of hepatogenesis. Knockdown of the four RA receptors revealed that all receptors affect liver formation, however specific receptors exert differential effects. Rargb knockdown...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Patterning
Share to Embryo, Nonmammalian

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mesoderm

Share to Models, Animal

Share to Nodal Protein

Share to Receptors, Retinoic Acid

Share to Tretinoin

Share to Zebrafish Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 22982668
DOI: 10.1016/j.ydbio.2012.09.001
PMCID: PMC3697125

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rargb regulates organ laterality in a zebrafish model of right atrial isomerism.PMID 22982668Read ↗

Classification of left-right patterning defects in zebrafish, mice, and humans.Semantic proximity Read ↗

Molecular basis of left-right asymmetry.Semantic proximity Read ↗

Knowing left from right: the molecular basis of laterality defects.Semantic proximity Read ↗

Formation and malformation of the vertebrate left-right axis.Semantic proximity Read ↗

Gap junctions are involved in the early generation of left-right asymmetry.Semantic proximity Read ↗

Recessively inherited right atrial isomerism caused by mutations in growth/differentiation factor 1 (GDF1).Semantic proximity Read ↗

Understanding laterality disorders and the left-right organizer: Insights from zebrafishSemantic proximity Read ↗

The Axenfeld-Rieger Syndrome Gene FOXC1 Contributes to Left-Right Patterning.Semantic proximity Read ↗

Breaking symmetry: a clinical overview of left-right patterning.Semantic proximity Read ↗

Left-right pattern of cardiac BMP4 may drive asymmetry of the heart in zebrafish.Semantic proximity Read ↗

Disorders of left-right asymmetry: heterotaxy and situs inversus.Semantic proximity Read ↗

Inhibition of Jagged-mediated Notch signaling disrupts zebrafish biliary development and generates multi-organ defects compatible with an Alagille syndrome phenocopySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.