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Article

The role of hMLH3 in familial colorectal cancer.

Cancer research - 15 Apr 2003

Liu Hong-Xu, Zhou Xiao-Lei, Liu Tao, Werelius Barbro, Lindmark Gudrun, Dahl Niklas, Lindblom Annika

Abstract excerpt

Hereditary nonpolyposis colorectal cancer (HNPCC) is commonly associated with at least three currently known DNA mismatch repair genes: (a) hMSH2; (b) hMLH1; and (c) hMSH6. A majority of HNPCC families has identifiable mutations in hMLH1 and hMSH2. When these mutations cause an inherited risk of colorectal cancer, they are also most often associated with microsatellite instability in the tumors. Recently, hMLH3...

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PMID: 12702580

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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