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Article

[Centrosome isolation from cultured bladder cancer cells--p53 mutation and centrosome hyperamplification].

Hinyokika kiyo. Acta urologica Japonica - 1 Feb 2003

Kawamura Kenji, Moriyama Manabu, Suga Koudai, Shiba Nobuyuki, Tanaka Tatsuro, Ikeda Ryosuke, Suzuki Koji

Abstract excerpt

Centrosome hyperamplification occurs frequently in human cancers, and is the major contributing factor for chromosomal instability and aneuploidy. We examined centrosome hyperamplification in bladder cancer cell lines. Samples were incubated with antibodies to the centrosome protein gamma-tubulin. The cell line (RT-4), which has a wild-type p53 status, showed a well-regulated centrosome replication cycle. On the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12696185

Genes

CDK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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