Article
Genetic variation in the ATP-binding cassette transporter gene ABCG2 (BCRP) in a Swedish population.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences - 1 Apr 2003
Bäckström Gunilla, Taipalensuu Jan, Melhus Håkan, Brändström Helena, Svensson Ann-Cathrin, Artursson Per, Kindmark Andreas
Abstract excerpt
The ATP-binding cassette transporter ABCG2 (also named breast cancer resistance protein, BCRP) functions as a drug efflux transporter and is expressed at high levels in the human small intestine. The aim of this study was to screen the human ABCG2 gene for genetic variation. The regions of the gene most likely to affect function, namely the coding parts, exon/intron boundaries, 5' untranslated region and 3'...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
