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Article

HLA genes associated with autoimmunity and progression to disease in type 1 diabetes.

Tissue antigens - 1 Feb 2003

Tait B D, Colman P G, Morahan G, Marchinovska L, Dore E, Gellert S, Honeyman M C, Stephen K, Loth A

Abstract excerpt

Insulin dependent diabetes mellitus (type I DM) is caused by an autoimmune process which culminates in destruction of pancreatic beta cells with resultant loss of insulin production. Preceding the clinical diagnosis of type I DM is a preclinical stage characterized by autoantibodies to insulin, glutamic acid decarboxylase (GAD) and a tyrosine phosphatase-like molecule (IA-2). We have studied both HLA class I and...

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Source

Identifiers

PMID: 12694582
DOI: 10.1034/j.1399-0039.2003.00013.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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