Article
Genetics of Type 1 diabetes mellitus.
Diabetes, nutrition & metabolism - 1 Feb 1999
Friday R P, Trucco M, Pietropaolo M
Abstract excerpt
Type 1 diabetes or insulin-dependent diabetes mellitus (IDDM) is the archetypal example of a T cell-mediated autoimmune disease characterised by selective destruction of a single cell type: the insulin-producing beta-cells of the pancreatic islets of Langerhans. The pathogenic equation for IDDM presents a complex interrelation of genetic and environmental factors, most of which have yet to be identified. Based on...
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