Article
Genetics of type 1A (immune mediated) diabetes.
Journal of autoimmunity - 1 Sept 2003
Melanitou Evie, Fain Pam, Eisenbarth George S
Abstract excerpt
Type 1A (immune mediated) diabetes is genetically heterogeneous with important examples for man and animal models with major mutations (autosomal recessive and X-linked recessive) identified as well as oligogenic/polygenic inheritance. For the most common forms of type 1A diabetes alleles of DQ and DR within the major histocompatibility complex are important determinants of disease and allow identification of...
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