Article
Gene polymorphisms, inflammatory diseases and cancer.
The Proceedings of the Nutrition Society - 1 Nov 2002
Howell W Martin, Calder Philip C, Grimble Robert F
Abstract excerpt
Genes whose products play a critical role in regulation of the immune response include the human leucocyte antigen (HLA) and cytokine families of genes. The HLA genes are the most polymorphic found in the human genome, and the bulk of this polymorphism results in functional differences in expressed HLA molecules, resulting in inter-individual differences in presentation of peptide antigens to T-cells. In...
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