Article
Genetics of inflammatory bowel disease. The candidate gene approach: susceptibility versus disease heterogeneity.
Digestive diseases (Basel, Switzerland) - 1 Jan 2000
Peña A S
Abstract excerpt
Ulcerative colitis and Crohn's disease are complex diseases of unknown etiology. Several genes are involved in the susceptibility. These genes are necessary to suffer from these diseases but not sufficient. Environmental factors trigger the inflammatory response. Evidence is accumulating that this response is abnormal in these patients. Therefore, the study of genes that are involved in the regulation of the...
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