Article
Collagenous Colitis Is Associated With HLA Signature and Shares Genetic Risks With Other Immune-Mediated Diseases.
Gastroenterology - 1 Aug 2020
Stahl Eli, Roda Giulia, Dobbyn Amanda, Hu Jianzhong, Zhang Zhongyang, Westerlind Helga, Bonfiglio Ferdinando, Raj Towfique, Torres Joana, Chen Anli, Petras Robert, Pardi Darrell S, Iuga Alina C, Levi Gabriel S, Cao Wenqing, Jain Prantesh, Rieder Florian, Gordon Ilyssa O, Cho Judy H, D'Amato Mauro, Harpaz Noam, Hao Ke, Colombel Jean Frederic, Peter Inga
Abstract excerpt
BACKGROUND & AIMS: Collagenous colitis (CC) is an inflammatory bowel disorder with unknown etiopathogenesis involving HLA-related immune-mediated responses and environmental and genetic risk factors. We carried out an array-based genetic association study in a cohort of patients with CC and investigated the common genetic basis between CC and Crohn's disease (CD), ulcerative colitis (UC), and celiac disease....
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