Article
Lipoprotein lipase (LPL) gene variation and progression of carotid artery plaque.
Stroke - 1 May 2003
Spence J David, Ban Matthew R, Hegele Robert A
Abstract excerpt
BACKGROUND AND PURPOSE: Coding single nucleotide polymorphisms (cSNPs) in the lipoprotein lipase (LPL) gene have been associated with lipoprotein phenotypes and vascular disease risk. We studied the association between LPL cSNPs and a novel noninvasive measure of disease, namely, cross-sectional carotid plaque area (CPA) on B-mode ultrasound. METHODS: Four hundred fifty-two patients from an atherosclerosis...
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