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Article

S447X variant of the lipoprotein lipase gene, lipids, and risk of coronary heart disease in 3 prospective cohort studies.

American heart journal - 1 Feb 2009

Jensen Majken K, Rimm Eric B, Rader Daniel, Schmidt Erik B, Sørensen Thorkild I A, Vogel Ulla, Overvad Kim, Mukamal Kenneth J

Abstract excerpt

BACKGROUND: Lipoprotein lipase (LPL) has a prominent role in the metabolism of triglycerides (TGs) and high-density lipoprotein cholesterol (HDL-C) and is a potential interesting target for the development of antiatherogenic treatment. To provide deeper insight into the role of natural variation in this gene, we investigated the association between the LPL S447X variant with lipids and risk of coronary heart...

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Source

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Identifiers

PMID: 19185650
DOI: 10.1016/j.ahj.2008.10.008
PMCID: PMC3183417

Genes

LPL
NHS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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