Article
Lipoprotein lipase gene mutations, plasma lipid levels, progression/regression of coronary atherosclerosis, response to therapy, and future clinical events. Lipoproteins and Coronary Atherosclerosis Study.
Atherosclerosis - 1 Jun 1999
Sing K, Ballantyne C M, Ferlic L, Brugada R, Cushman I, Dunn J K, Herd J A, Pownall H J, Gotto A M, Marian A J
Abstract excerpt
Mutations in human lipoprotein lipase (LPL) gene are potential risk factors for susceptibility to coronary artery disease (CAD). The objectives of this study were to determine the influence LPL mutations Asn291Ser and Ser447Ter on plasma lipid levels, regression and progression of CAD, clinical events rate, and response to fluvastatin therapy in the Lipoprotein and Coronary Atherosclerosis Study (LCAS)...
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