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Article

Increased plasma levels of matrix metalloproteinase-9 in patients with Alzheimer's disease.

Neurochemistry international - 1 Aug 2003

Lorenzl Stefan, Albers David S, Relkin Norman, Ngyuen Terry, Hilgenberg Sarah L, Chirichigno Jason, Cudkowicz Merit E, Beal M Flint

Abstract excerpt

Matrix metalloproteinases (MMPs) may play a role in the pathophysiology of Alzheimer's disease (AD). MMP-9 and tissue inhibitors of metalloproteinases (TIMPs) are elevated in postmortem brain tissue of AD patients. MMPs and TIMPs are found in neurons, microglia, vascular endothelial cells and leukocytes. The aim of this study was to determine whether circulating levels of MMP-2, MMP-9, TIMP-1 and TIMP-2 are...

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Identifiers

PMID: 12689599
DOI: 10.1016/s0197-0186(03)00004-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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