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Article

Serum matrix metalloproteinase-9 activity is dysregulated with disease progression in the mutant SOD1 transgenic mice.

Neuromuscular disorders : NMD - 1 Apr 2010

Soon Cynthia P W, Crouch Peter J, Turner Bradley J, McLean Catriona A, Laughton Katrina M, Atkin Julie D, Masters Colin L, White Anthony R, Li Qiao-Xin

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is an adult-onset fatal neurodegenerative disorder characterized by progressive deterioration of motor neurons in the spinal cord, brainstem, and cerebral cortex. Matrix metalloproteinase-9 (MMP-9) is proposed to be a biomarker for ALS due to a potential pathological role in the disease. However, despite numerous studies, it is still unclear whether there is a direct...

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Source

Identifiers

PMID: 20097566
DOI: 10.1016/j.nmd.2009.11.015

Genes

SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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