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Article

The role of MMP genes in recurrent depressive disorders and cognitive functions

9 Feb 2016

Abstract excerpt

OBJECTIVE: Among the 28 metalloproteinases described so far, 23 can be found in the human organism, but only few are expressed in the human brain. The main objective of this study was to analyse the relationship between MMP-2, MMP-9 and TIMP-2 gene expression and cognitive performance. METHODS: The study comprised 234 subjects: patients suffering from recurrent depressive disorder (rDD, n=139) and healthy...

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PMID: 26856768
DOI: 10.1017/neu.2015.72

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