Article
The synaptojanin-like protein Inp53/Sjl3 functions with clathrin in a yeast TGN-to-endosome pathway distinct from the GGA protein-dependent pathway.
Molecular biology of the cell - 1 Apr 2003
Ha Seon-Ah, Torabinejad Javad, DeWald Daryll B, Wenk Markus R, Lucast Louise, De Camilli Pietro, Newitt Richard A, Aebersold Ruedi, Nothwehr Steven F
Abstract excerpt
Yeast TGN resident proteins that frequently cycle between the TGN and endosomes are much more slowly transported to the prevacuolar/late endosomal compartment (PVC) than other proteins. However, TGN protein transport to the PVC is accelerated in mutants lacking function of Inp53p. Inp53p contains a SacI polyphosphoinositide phosphatase domain, a 5-phosphatase domain, and a proline-rich domain. Here we show that...
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