Article
A novel mechanism for localizing membrane proteins to yeast trans-Golgi network requires function of synaptojanin-like protein.
Molecular biology of the cell - 1 Oct 2001
Ha S A, Bunch J T, Hama H, DeWald D B, Nothwehr S F
Abstract excerpt
Localization of resident membrane proteins to the yeast trans-Golgi network (TGN) involves both their retrieval from a prevacuolar/endosomal compartment (PVC) and a "slow delivery" mechanism that inhibits their TGN-to-PVC transport. A screen for genes required for the slow delivery mechanism uncovered INP53, a gene encoding a phosphoinositide phosphatase. A retrieval-defective model TGN protein, A(F-->A)-ALP, was...
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