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Article

Mutation and methylation of hMLH1 in gastric carcinomas with microsatellite instability.

World journal of gastroenterology - 1 Apr 2003

Fang Dian-Chun, Wang Rong-Quan, Yang Shi-Ming, Yang Jian-Ming, Liu Hai-Feng, Peng Gui-Yong, Xiao Tian-Li, Luo Yuan-Hui

Abstract excerpt

AIM: To appraise the correlation of mutation and methylation of hMSH1 with microsatellite instability (MSI) in gastric cancers. METHODS: Mutation of hMLH1 was detected by Two-dimensional electrophoresis (Two-D) and DNA sequencing; Methylation of hMLH1 promoter was measured with methylation-specific PCR; MSI was analyzed by PCR-based methods. RESULTS: Sixty-eight cases of sporadic gastric carcinoma were studied...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12679904
DOI: 10.3748/wjg.v9.i4.655
PMCID: PMC4611422

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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