Article
[Association of homozygosity for short allele (S) of heavy neurofilament subunit gene with motor neuron disease and oxidative stress development].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova - 1 Jan 2003
Skvortsova V I, Limborskaia S A, Slominskiĭ P A, Brusov O S, karakhan V B, Gerasimova M M, Levitskaia N I, Levitskiĭ G N, Shadrina M I, Kondrat'eva E A, Alekhin A V, Serdiuk A V, Botvinko T M
Abstract excerpt
We analyzed distribution of heavy neurofilament (NF-H) gene S/L-polymorphic variants in 51 patients with idiopathic motor neuron disease (MND) vs control group and in relation to superoxide dismutases (SODs) activity and thiobarbituric acid reactive substances (TBARS) level in cerebrospinal fluid (CSF), erythrocytes and blood serum. We found that individuals with homozygosity for NF-H gene short allele...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.