Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neurodegenerative disease. Oxidative stress and motorneuron disease.

Current biology : CB - 1 Nov 1994

Sendtner M, Thoenen H

Abstract excerpt

Transgenic mice carrying mutated Cu/Zn superoxide dismutase genes provide insights into the pathogenesis of human motorneuron diseases and may be useful as models in the development and testing of therapies.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mice
Share to Mice, Transgenic
Share to Models, Molecular
Share to Molecular Structure

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Nerve Degeneration

Share to Oxidative Stress

Share to Superoxide Dismutase

Source

Identifiers

PMID: 7874490
DOI: 10.1016/s0960-9822(00)00237-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neurodegenerative disease. Oxidative stress and motorneuron disease.PMID 7874490Read ↗

Mitochondrial defects in transgenic mice expressing Cu,Zn superoxide dismutase mutations: the role of copper chaperone for SOD1.Semantic proximity Read ↗

Oxidative stress and motor neurone disease.Semantic proximity Read ↗

A Proposed Mechanism for Neurodegeneration in Movement Disorders Characterized by Metal Dyshomeostasis and Oxidative Stress.Semantic proximity Read ↗

Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS.Semantic proximity Read ↗

Superoxide dismutase, aging, and degenerative disease.Semantic proximity Read ↗

Oxidative Stress in Transgenic Mice with Oligodendroglial α-Synuclein Overexpression Replicates the Characteristic Neuropathology of Multiple System AtrophySemantic proximity Read ↗

Oxidative stress in ALS: key role in motor neuron injury and therapeutic target.Semantic proximity Read ↗

Highlight Commentary on "Redox proteomics analysis of oxidatively modified proteins in G93A-SOD1 transgenic mice--a model of familial amyotrophic lateral sclerosis".Semantic proximity Read ↗

Mutation of superoxide dismutase elevates reactive species: comparison of nitration and oxidation of proteins in different brain regions of transgenic mice with amyotrophic lateral sclerosis.Semantic proximity Read ↗

Neuronal deletion of MnSOD in mice leads to demyelination, inflammation and progressive paralysis that mimics phenotypes associated with progressive multiple sclerosis.Semantic proximity Read ↗

Interplay of Cu,Zn superoxide dismutase and nitric oxide synthase in neurodegenerative processes.Semantic proximity Read ↗

Pathogenic mechanisms in familial amyotrophic lateral sclerosis due to mutation of Cu, Zn superoxide dismutase.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.