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Article

Transcriptional profiling of the clpX mutant in Bacillus anthracis reveals regulatory connection with the lrgAB operon.

Microbiology (Reading, England) - 1 Apr 2018

Claunch Kevin M, Bush Madeline, Evans Christopher R, Malmquist Jacob A, Hale Matthew C, McGillivray Shauna M

Abstract excerpt

ClpX functions as either an independent chaperone or a component of the ClpXP protease, a conserved intracellular protease that acts as a global regulator in the bacterial cell by degrading regulatory proteins, stress response proteins and rate-limiting enzymes. Previously, we found that loss of clpX in Bacillus anthracis Sterne leads to increased susceptibility to antimicrobial agents that target the cell...

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Identifiers

PMID: 29473820
DOI: 10.1099/mic.0.000628

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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