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Article

Genetic footprinting of the HIV co-receptor CCR5: delineation of surface expression and viral entry determinants.

Virology - 1 Mar 2003

Quinonez Ricardo, Sinha Indu, Singh Ila R, Sutton Richard E

Abstract excerpt

Human immunodeficiency virus type 1 (HIV-1) utilizes CD4 as a primary receptor for viral entry and any of several 7-transmembrane chemokine receptors, including CCR5, as a co-receptor. Previous studies have demonstrated that multiple extracellular domains (ECDs) of CCR5 contribute to co-receptor function; here we applied genetic footprinting to CCR5 to confirm and extend those investigations. In genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12667818
DOI: 10.1016/s0042-6822(02)00032-6

Genes

CCR5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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