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Article

The Expanding Therapeutic Perspective of CCR5 Blockade

12 Jan 2018

Abstract excerpt

CCR5 and its interaction with chemokine ligands have been crucial for understanding and tackling HIV-1 entry into target cells. However, over time, CCR5 has witnessed an impressive transition from being considered rather unimportant in physiology and pathology to becoming central in a growing number of pathophysiological conditions. It now turns out that the massive efforts devoted to combat HIV-1 entry by...

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PMID: 29375583
DOI: 10.3389/fimmu.2017.01981

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