Article
The proapoptotic factor Nix is coexpressed with Bcl-xL during terminal erythroid differentiation
1 Apr 2003
Abstract excerpt
Transcriptional profiles of cultured primary human erythroid cells were examined to identify those genes involved in the control of erythroid growth during the terminal phase of maturation. Our in silico screening strategy indicated that a hypoxia-inducible proapoptotic member of the Bcl-2 gene family called Nix is expressed during erythropoiesis. We next performed Northern blot analyses and determined that the...
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